General anaesthesia and acute intermittent porphyria: a case presentation

Sub-title
AuthorsN Borg
D Spiteri
J Gonzi
AbstractWe present a 35 year old lady known to suffer from ACUTE INTERMITTENT PORPHYRIA who was referred for General Anaesthesia for laparotomy in view of persisting abdominal pain. This clinical diagnosis of porphyria had been previously confirmed by elevated urinary porphyrins on more than one occasion. Prior to our encounter with the patient, she had been administered GA on four separate occasions over a number of years. Following each and every GA she was complaining of severe abdominal pain. We describe each GA and the drugs that were given on each occasion: Our anaesthetic technique varied with the knowledge that the patient has acute intermittent porphyria and we summarise every drug that was given before, during and after our anaesthetic. We also discuss the monitoring used during the whole procedure. Our patient did not show any signs of distress throughout anaesthesia and she made an uneventful recovery with no complaints of abdominal pain or of any other sort

Published in:
JournalMalta Medical Journal
Volume15 Issue 1-2/suppl. 2003
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Date
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Key wordsacute intermittent porphyria, case report, general anaesthesia

Compiled by: Dr. I. Stabile    Dr. J. Pace