Thyroid status in subjects on thyroid replacement treatment

Sub-title
AuthorC Azzopardi
AbstractAims and Objectives: To determine the proportion of subjects on thyroid replacement treatment (TRT) who achieve normal (biochemical) thyroid status, and to compare this to an audit standard set in the United Kingdom. Design: Cross-sectional study. Participants and setting: Subjects attending the medical consultant clnic at Qormi, Rabat and Birkirkara health centres for follow-up and monitoring of TRT. Period: August 2003 to July 2004 Data collected: 1. laboratory results of routine thyroid function tests (TFT) 2. demographic data from the case notes - age, sex 3. date of TFT and date of follow-up visit 4. dose of thyroxine at the time of the TFT. Data analysis: Results of TFTs were categorised into (i) normal thyroid stimulating hormone (TSH) level (ii) TSH outside normal reference range - high or low; free thyroxine and free tri-iodothyronine were also recorded when available. Results: Two thirds of subjects on TRT had a TSH within the normal reference range (0.4-4 ?U/ml). Conclusion: This proportion is below the 90 per cent audit standard set in the United Kingdom for control of TRT, but is similar to results of audits published by community practices in the same country.

Published in:
JournalMalta Medical Journal
Volume15 Issue 1-2/suppl. 2003
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Date
Link to journal

Key wordsaudit, thyroxine, thyroid status

Compiled by: Dr. I. Stabile    Dr. J. Pace